Fraker D L
University of Pennsylvania, Department of Surgery, Philadelphia 19104, USA.
Curr Opin Oncol. 1997 Mar;9(2):183-8. doi: 10.1097/00001622-199703000-00014.
The mainstay of treatment of cutaneous melanoma is surgical excision. Excision of the primary disease, lymph node metastases, and in some instances, distant metastases is the only therapeutic strategy that leads to long-term disease-free survival with rare exceptions. Surgical treatment of melanoma can be divided into therapy of the primary lesion, treatment of the lymph nodes, treatment of distant metastases, and treatment of in-transit disease by regional administration of intravascular chemotherapeutics. The current recommendations for each of these four areas is discussed in this review.
皮肤黑色素瘤治疗的主要方法是手术切除。切除原发性疾病、淋巴结转移灶,在某些情况下切除远处转移灶,是唯一能带来长期无病生存的治疗策略,极少有例外情况。黑色素瘤的手术治疗可分为原发性病灶治疗、淋巴结治疗、远处转移灶治疗以及通过血管内化疗药物区域给药治疗途中转移病灶。本综述将讨论这四个领域目前的建议。