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[长期未控制的抗高血压治疗对轻度和中度动脉高血压患者左心室肥厚超声心动图征象的影响]

[The effect of long-term uncontrolled antihypertensive therapy on the echocardiographic signs of left-heart hypertrophy in patients with mild and moderate arterial hypertension].

作者信息

Lerman O V, Metelitsa V I, Filatova N P, Duda S G, Malysheva N V, Vygodin V A

出版信息

Ter Arkh. 1997;69(1):43-6.

PMID:9163049
Abstract

The data are presented on the absence of a stable positive trend in echocardiographic characteristics of the left heart and intracardiac hemodynamics after 8 months of controlled antihypertensive therapy, 12-month follow-up and uncontrolled outpatient treatment. 12 months after discontinuation of controlled antihypertensive therapy arterial pressure was much higher than it was at the end of the treatment in patients taking antihypertensive drugs irregularly or not taking them at all. Intracardiac hemodynamics returned to the baseline. As shown by echo-CG, frequency of left ventricular hypertrophy 12 months after the end of antihypertensive treatment rose from 25.8 to 45.2% (p < 0.01), of right ventricular hypertrophy from 14.5 to 17.7%.

摘要

数据显示,在进行8个月的控制性降压治疗、12个月的随访以及非控制性门诊治疗后,左心超声心动图特征和心内血流动力学不存在稳定的正向趋势。在停止控制性降压治疗12个月后,血压在未规律服用降压药或根本未服用降压药的患者中比治疗结束时高得多。心内血流动力学恢复到基线水平。超声心动图显示,降压治疗结束12个月后,左心室肥厚的发生率从25.8%升至45.2%(p<0.01),右心室肥厚的发生率从14.5%升至17.7%。

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