Sasaki H, Takishima T, Sasaki T
Jpn J Physiol. 1977;27(2):157-66. doi: 10.2170/jjphysiol.27.157.
The main bronchi of excised dog lobes were obstructed with beads, 5 to 6 cm from their origin so that they did not communicate with the peripheral air spaces. Both pulmonary artery and vein were cannulated and both pulmonary vascular pressures were controlled. With the lobe held at constant transpulmonary pressure, bronchial pressure-volume curves were studied during acute pulmonary vascular engorgement. The bronchial compliance was reduced at higher vascular pressure and the effect of vascular engorgement on the bronchial collapsibility was larger at higher transpulmonary pressure: bronchial compliance at vascular pressure-40 cm H2O at transpulmonary pressure 20, 10, 5, and 0 cm H2O respectively. We concluded that vascular engorgement increased parenchymal radial traction to the bronchi when the bronchi reduced its diameter, although it appeared that vascular engorgement resulted in little change in the lung elastic recoil pressure.
将切除的犬肺叶的主支气管在距其起源5至6厘米处用珠子阻塞，使其不与外周气腔相通。肺动脉和肺静脉均进行插管，并控制肺血管压力。在肺叶保持恒定的跨肺压时，研究急性肺血管充血期间的支气管压力-容积曲线。在较高的血管压力下，支气管顺应性降低，并且在较高的跨肺压下，血管充血对支气管塌陷性的影响更大：在跨肺压分别为20、10、5和0厘米水柱时，血管压力为40厘米水柱时的支气管顺应性。我们得出结论，当支气管直径减小时，血管充血增加了实质对支气管的径向牵引力，尽管血管充血似乎对肺弹性回缩压影响很小。
