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肝内胆管结石肝门部狭窄的外科治疗

Surgical treatment of hilar strictures in hepatolithiasis.

作者信息

Huang J F, Qian W, Peng G B

机构信息

Department of Hepatobiliary Surgery, Sun Yat-Sen University of Medical Sciences, Guangzhou, China.

出版信息

Hepatogastroenterology. 1997 Mar-Apr;44(14):322-7.

PMID:9164498
Abstract

BACKGROUND/AIMS: The management of biliary strictures in hepatolithiasis, particularly at the hilus of the liver including the right and left hepatic bile ducts and their confluence, presents a challenge for surgeons because of their difficult access for surgical procedures and the life-threatening consequences, such as unrelenting cholangitis, recurrent biliary calculi, liver abscess and septicemia they can cause. This study analyzed the response of a group of patients with hilar strictures undergoing different surgical operations to assess methods dealing with this condition.

PATIENTS AND METHODS

A total of 545 patients with hepatolithiasis were admitted to our hospital. Among them, 256 patients were found to have an association of high bile duct strictures. These were classified into three types based on the sites of the stricture, and operated on with different combined surgical procedures in accordance with the type of the strictures. After the operation, further assessment was made during a follow-up period of between 12 months to 6 years.

RESULTS

Postoperative morbidity and mortality were 15.7% (40/256) and 1.2% (3/256), respectively. Before discharge from the hospital, all patients underwent imaging investigation, and the retained stone rate was 20.3% (53/256). Of the 70% of patients (179/256) who were available for further assessment, 85% had good treatment results, were asymptomatic and required no medical treatment. A few patients got a poor result when symptoms of cholangitis occurred several times a year and required hospitalization.

CONCLUSIONS

Successful treatment of hilar strictures in hepatolithiasis depends on the correct localization of the strictures, and complete exposure of the biliary tract proximal to strictures as well as the appropriate selection of the surgical procedures.

摘要

背景/目的:肝内胆管结石合并胆管狭窄的处理,尤其是肝门部包括左右肝管及其汇合处的胆管狭窄,因其手术操作难度大以及可能导致如持续性胆管炎、复发性胆石症、肝脓肿和败血症等危及生命的后果,对外科医生而言是一项挑战。本研究分析了一组接受不同手术治疗的肝门部狭窄患者的治疗反应,以评估处理该病症的方法。

患者与方法

共有545例肝内胆管结石患者入住我院。其中,256例患者合并高位胆管狭窄。根据狭窄部位将其分为三种类型,并根据狭窄类型采用不同的联合手术方式进行治疗。术后,在12个月至6年的随访期内进行进一步评估。

结果

术后发病率和死亡率分别为15.7%(40/256)和1.2%(3/256)。出院前,所有患者均接受了影像学检查,结石残留率为20.3%(53/256)。在可进行进一步评估的70%的患者(179/256)中,85%的患者治疗效果良好,无症状且无需治疗。少数患者每年发生数次胆管炎症状且需要住院治疗,治疗效果较差。

结论

肝内胆管结石合并肝门部狭窄的成功治疗取决于狭窄部位的正确定位、狭窄近端胆道的充分显露以及手术方式的恰当选择。

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