Leahy M, Howell A
Department of Medical Oncology, Christie Hospital, Manchester.
Br J Hosp Med. 1997;57(4):141-4.
Paclitaxel was the first taxoid to become available. It was found to be an active anticancer agent but with significant toxicity. Docetaxel is a semisynthetic taxoid and the next of a fast-expanding class of drugs. Studies suggest that docetaxel may be more effective and less toxic than paclitaxel.
紫杉醇是首个可用的紫杉烷类药物。它被发现是一种有效的抗癌药物，但具有显著的毒性。多西他赛是一种半合成紫杉烷类药物，是快速发展的一类药物中的下一个。研究表明，多西他赛可能比紫杉醇更有效且毒性更小。
