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全腹腔镜胃底折叠术与部分腹腔镜胃底折叠术治疗胃食管反流病的比较

Comparison of total versus partial laparoscopic fundoplication in the management of gastroesophageal reflux disease.

作者信息

Karim S S, Panton O N, Finley R J, Graham A J, Dong S, Storseth C, Clifton J

机构信息

Department of Surgery, Vancouver and Delta Hospital, British Columbia, Canada.

出版信息

Am J Surg. 1997 May;173(5):375-8. doi: 10.1016/S0002-9610(97)00078-0.

Abstract

BACKGROUND AND METHODS

A comparison of total vs. partial laparoscopic fundoplication was conducted in 89 patients from July 92 to June 96. Parameters examined were operating room (OR) times, conversion rates, and perioperative complications. Patient satisfaction, control of symptoms, and late complications were assessed by follow-up at a mean of 6 and 15.4 months.

RESULTS

There were six conversions to open surgery resulting in 48 laparoscopic total (LTF) and 35 laparoscopic partial (25 anterior and 10 Toupet) fundoplications (LPF). The following results were obtained for each respectively: preop Demeester score 44 vs. 39; OR time 2.9 vs. 2.5 hours; length of stay 3.6 vs. 4.1 days; early morbidity 25% vs. 1%. There were no mortalities. At a mean follow-up of 6 months, new-onset dysphagia was present in 8 (17%) vs. 2 (8%), respectively (NS), and both total and partial fundoplications appeared successful in controlling symptoms (98% vs. 97%). At a mean follow-up of 15.4 months, heartburn was resolved or improved in 76% vs. 87% (NS); regurgitation was improved or resolved in 93% vs. 93%; and patient satisfaction with the procedure was present in 93% vs. 97% (NS). Persistent dysphagia was present in 7.3% vs. 10.3% (NS) of patients. Early satiety was present more often in the partial fundoplication group (56% vs. 83% P = .03).

CONCLUSIONS

Early follow-up suggests equal efficacy in controlling symptoms and in achieving patient satisfaction. A 6-month follow-up suggested a higher incidence of new dysphagia in the total fundoplication group; however, at 15-month follow-up there was no significant difference.

摘要

背景与方法

1992年7月至1996年6月期间,对89例患者进行了全腹腔镜胃底折叠术与部分腹腔镜胃底折叠术的比较。所检查的参数包括手术时间、中转率和围手术期并发症。通过平均6个月和15.4个月的随访评估患者满意度、症状控制情况和远期并发症。

结果

有6例中转开腹手术,最终有48例腹腔镜全胃底折叠术(LTF)和35例腹腔镜部分胃底折叠术(25例前位和10例Toupet术式)(LPF)。分别得到以下结果:术前德梅斯特评分44对39;手术时间2.9小时对2.5小时;住院时间3.6天对4.1天;早期发病率25%对1%。无死亡病例。平均随访6个月时,新发吞咽困难分别出现在8例(17%)对2例(8%)患者中(无显著性差异),全胃底折叠术和部分胃底折叠术在控制症状方面均显示成功(98%对97%)。平均随访15.4个月时,烧心症状缓解或改善的比例为76%对87%(无显著性差异);反流症状改善或缓解的比例为93%对93%;患者对手术的满意度为93%对97%(无显著性差异)。持续性吞咽困难出现在7.3%对10.3%的患者中(无显著性差异)。部分胃底折叠术组早期饱腹感出现更为常见(56%对83%,P = 0.03)。

结论

早期随访表明在控制症状和实现患者满意度方面疗效相当。6个月随访显示全胃底折叠术组新发吞咽困难发生率较高;然而,在15个月随访时无显著差异。

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