Fujimoto K, Suzawa M, Hanaoka M, Matsuzawa Y, Kubo K, Sekiguchi M, Hanyuda M
First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Mar;35(3):357-64.
A 61-year-old man suffering from severe pulmonary emphysema underwent lung volume reduction surgery on both upper lobes. By one year after surgery functional residual capacity had decreased by 2.5 L and FEV1 had increased by a factor of 2.4. Diaphragm excursion, as assessed by dynamic magnetic resonance imaging, had increased and ventilation and pulmonary gas exchange had improved. Performance on a 6-minute-walk test and exercise tolerance measured on a bicycle ergometer improved, and both peak VE and VO2 increased. Before surgery, pulmonary artery pressure Ppa and pulmonary capillary wedge pressure Pewp during exercise were abnormally high, but 6 months after the operation the increases in Ppa and Pcwp during exercise were markedly reduced.