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对80岁及以上双胞胎认知能力的重大基因影响。

Substantial genetic influence on cognitive abilities in twins 80 or more years old.

作者信息

McClearn G E, Johansson B, Berg S, Pedersen N L, Ahern F, Petrill S A, Plomin R

机构信息

Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, PA 16802, USA.

出版信息

Science. 1997 Jun 6;276(5318):1560-3. doi: 10.1126/science.276.5318.1560.

Abstract

General and specific cognitive abilities were studied in intact Swedish same-sex twin pairs 80 or more years old for whom neither twin had major cognitive, sensory, or motor impairment. Resemblance for 110 identical twin pairs significantly exceeded resemblance for 130 fraternal same-sex twin pairs for all abilities. Maximum-likelihood model-fitting estimates of heritability were 62 percent for general cognitive ability, 55 percent for verbal ability, 32 percent for spatial ability, 62 percent for speed of processing, and 52 percent for memory. There was also evidence for the significant influence of idiosyncratic experience as the environmental component that most determines individual differences in cognitive abilities late in life.

摘要

对80岁及以上的瑞典同性双胞胎进行了一般认知能力和特殊认知能力的研究,这些双胞胎均未出现严重的认知、感官或运动障碍。在所有能力方面,110对同卵双胞胎的相似性显著超过130对异卵同性双胞胎的相似性。遗传力的最大似然模型拟合估计值为:一般认知能力62%,语言能力55%,空间能力32%,处理速度62%,记忆能力52%。也有证据表明,特质性经历作为环境因素,对晚年认知能力的个体差异起着最主要的决定作用。

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