Berthault F, Kintz P, Tracqui A, Mangin P
Institut de Médecine Légale, Strasbourg, France.
J Anal Toxicol. 1997 May-Jun;21(3):228-31. doi: 10.1093/jat/21.3.228.
We report the first case in the literature of fatal betaxolol (Kerlone) self-poisoning. After a single-step liquid-liquid alkaline extraction, betaxolol was identified by a high-performance liquid chromatographic-diode array detection screening procedure and then quantitated in cardiac blood, heart, brain, muscle, spleen, stomach contents, duodenum contents, liver, and kidney. The blood betaxolol concentration was 36 mg/L.
我们报告了文献中首例致命性倍他洛尔（凯尔心安）自服中毒病例。经一步液 - 液碱性萃取后，通过高效液相色谱 - 二极管阵列检测筛选程序鉴定出倍他洛尔，随后对心血、心脏、脑、肌肉、脾脏、胃内容物、十二指肠内容物、肝脏和肾脏进行定量分析。血液中倍他洛尔浓度为36毫克/升。
