Goldmann R, Bornscheuer A, Kirchner E
Abteilung Anästhesiologie, Medizinische Hochschule Hannover.
Anasthesiol Intensivmed Notfallmed Schmerzther. 1997 Feb;32(2):98-100. doi: 10.1055/s-2007-995016.
Pain is a well known complication of propofol injection. Many methods are described to reduce it but often empirical ways are used. In this study we attempt to determine the effects of premixing propofol with lidocaine or to preinjecting lidocaine in a hand vein in combination with using a tourniquet before we applicated propofol. Our study shows that both ways are able to reduce the injection pain but premixing with lidocaine 0.05% is less effective than giving a bolus of lidocaine before the propofol injection.
疼痛是丙泊酚注射众所周知的并发症。有许多方法被描述用于减轻疼痛,但通常采用的是经验性方法。在本研究中,我们试图确定将丙泊酚与利多卡因预混合,或在手部静脉预先注射利多卡因并在注射丙泊酚前使用止血带的效果。我们的研究表明,两种方法都能够减轻注射疼痛,但与在注射丙泊酚前推注一剂利多卡因相比,与0.05%利多卡因预混合的效果较差。