Alezrah C, Monteil A L, Faillie X, Hatem O
Service de Réanimation médicale, Centre hospitalier général, Perpignan.
Encephale. 1997 Jan-Feb;23(1):72-5.
Creutzfeldt-Jakob disease is relatively poorly documented in psychiatry. An observation will be presented concerning a 69 years old patient admitted for conduct disorder and prosecution delirium. In fact, the symptomatology associated dementia, transient confusion, parkinsonism, ataxia and abnormal movements. In the checkup the electroencephalogram gave us an important orientation for diagnosis. After a thoracic trauma the patient was admitted in an intensive care unit with a positive pressure ventilation. His general condition worsened until he died. Brain histic exploration and PRP gene analysis confirmed the diagnosis. Even if there is no efficient treatment, such a diagnosis has to be done in order to take prophylactic measures and conduct epidemiological surveys.
克雅氏病在精神病学领域的文献记载相对较少。现将一名69岁因品行障碍和诉讼性谵妄入院的患者的观察情况予以呈现。事实上,其症状包括痴呆、短暂性意识模糊、帕金森症、共济失调及异常运动。检查时,脑电图为诊断提供了重要线索。胸部创伤后,患者入住重症监护病房并接受正压通气。其总体状况不断恶化直至死亡。脑部组织检查及朊蛋白基因分析确诊了该病。即便尚无有效治疗方法,但做出此类诊断以便采取预防措施并开展流行病学调查仍很有必要。