Lalouschek W, Aull S, Deecke L, Lesch O M, Schnider P, Zeiler K
Klinik für Neurologie, Universität Wien.
Fortschr Med. 1997 Mar 10;115(7):35-8.
Cocaine abuse as a risk factor for acute cerebrovascular events has received too little attention, in particular in young patients. Cocaine hydrochloride causes mainly intracerebral and subarachnoidal bleeding, while crack (freebase) causes intracranial hemorrhage and ischemic infarctions with equal frequency. Although no specific antidote is known, an attempt should be made to detect the substance or its metabolites in the urine so as to provide optimal management, and encourage the patient to seek expert counselling.
可卡因滥用作为急性脑血管事件的一个风险因素,受到的关注过少,尤其是在年轻患者中。盐酸可卡因主要导致脑内和蛛网膜下腔出血,而快克(游离碱)导致颅内出血和缺血性梗死的频率相同。尽管尚无已知的特效解毒剂,但应尝试检测尿液中的该物质或其代谢物,以便提供最佳治疗,并鼓励患者寻求专业咨询。