Nolte K B, Gelman B B
Office of the Chief Medical Examiner, State of North Carolina, Chapel Hill.
Arch Pathol Lab Med. 1989 Jul;113(7):812-3.
With the current epidemic of cocaine abuse, there have been many clinical reports of cocaine toxicity, including stroke. Autopsy findings were reported in only one case of intracerebral hemorrhage associated with cocaine abuse. We describe the autopsy toxicological findings in a case of sudden death in a young person due to intracerebral hemorrhage associated with cocaine abuse. In view of the present epidemic of cocaine abuse, cocaine toxicity should be considered in the differential diagnosis of intracerebral hemorrhage. We suggest that the pharmacodynamic effects of cocaine on the cerebral vasculature is the most likely cause.
随着当前可卡因滥用的流行，出现了许多关于可卡因毒性的临床报告，包括中风。仅有一例与可卡因滥用相关的脑出血病例报告了尸检结果。我们描述了一例因与可卡因滥用相关的脑出血导致年轻人猝死的尸检毒理学发现。鉴于目前可卡因滥用的流行情况，在脑出血的鉴别诊断中应考虑可卡因毒性。我们认为可卡因对脑血管的药效学作用是最可能的原因。
