Chapuis G
Service de chirurgie, CHUV, Lausanne.
Rev Med Suisse Romande. 1997 Feb;117(2):131-5.
In addition to the excision of the tumor itself, the surgical management of carcinomas includes the removal of regional lymph nodes or lymphadenectomy. The lymphatic system is not the only path of metastatic spread but it is often the main one. The percentage of tumors with lymph node metastases varies with the location and above all with the extent of the tumor at the time of surgery. For example, axillary metastases are much less frequent in cancers discovered by screening mammography than in those with clinical signs. Lymphadenectomy is important for loco-regional control and to determine the prognosis which may dictate adjuvant therapy. In some patients, it also contributes to the cure of their disease by removing lymph nodes metastases that sometimes can only be detected by immunohistochemistry. Lymphadenectomy should be very extensive when done with curative intent and very selective when performed only for prognostic information.
除了切除肿瘤本身外,癌的手术治疗还包括切除区域淋巴结或进行淋巴结清扫术。淋巴系统并非转移扩散的唯一途径,但往往是主要途径。发生淋巴结转移的肿瘤百分比因肿瘤位置而异,最重要的是因手术时肿瘤的范围而异。例如,通过乳腺钼靶筛查发现的癌症发生腋窝转移的频率远低于有临床症状的癌症。淋巴结清扫术对于局部区域控制和判断预后很重要,而预后可能决定辅助治疗方案。在一些患者中,通过切除有时只能通过免疫组织化学检测到的淋巴结转移灶,淋巴结清扫术也有助于治愈他们的疾病。当以治愈为目的进行淋巴结清扫术时应非常广泛,而仅为获取预后信息时则应非常有选择性。