Wanaratna L, Sinawat S, Vasantavisuthi E, Thaineua V
Institute of Nutrition, Mahidol University, Nakornpathom.
J Med Assoc Thai. 1997 Mar;80(3):139-46.
Previous surveys have suggested that preschool children in the North and Northeast of Thailand are at risk of inadequate vitamin A nutriture. Therefore, vitamin A status was assessed in 996 children aged 2-6 years in the North and Northeast Thailand during the dry (Feb.-April) and rainy (Sept.-Nov.) seasons. Approximately 1 per cent of samples during both periods exhibited serum retinol concentrations below 10 mcg/dl with means (+/-SD) concentration of 29 +/- 9.8 mcg/dl in the dry season and 37 +/- 15.4 mcg/dl in the rainy season. About one fifth of the studied children showed abnormal CIC and depleted liver stores (RDR > 20%). High risk areas were ranked and corresponded well by these 2 indicators. Therefore, it is concluded that the magnitude of the problem estimated by RDR and CIC are a more precise measurement of marginal vitamin A status than serum vitamin A level alone and about one-fifth of preschool children in the North and Northeast regions of Thailand experience subclinical vitamin A deficiency.
以往的调查表明，泰国北部和东北部的学龄前儿童存在维生素A营养不足的风险。因此，在泰国北部和东北部对996名2至6岁儿童在旱季（2月至4月）和雨季（9月至11月）进行了维生素A状况评估。两个时期约1%的样本血清视黄醇浓度低于10 mcg/dl，旱季平均（±标准差）浓度为29±9.8 mcg/dl，雨季为37±15.4 mcg/dl。约五分之一的受试儿童表现出异常的CIC和肝脏储备耗尽（RDR>20%）。高危地区通过这两个指标进行了排名且吻合度良好。因此，得出结论，通过RDR和CIC评估的问题严重程度比单独的血清维生素A水平更能精确衡量边缘性维生素A状况，泰国北部和东北部约五分之一的学龄前儿童存在亚临床维生素A缺乏。
