短期气味记忆：大鼠外侧嗅束后横断的影响

Short-term odor memory: effects of posterior transection of the lateral olfactory tract in the rat.

作者信息

Thanos P K, Slotnick B M

机构信息

Department of Psychology, The American University, Washington, DC 20016, USA.

出版信息

Physiol Behav. 1997 Jun;61(6):903-6. doi: 10.1016/s0031-9384(97)00003-6.

DOI:10.1016/s0031-9384(97)00003-6

PMID:9177565

Abstract

Rats were trained on a series of novel 2-odor discrimination problems before and after combined unilateral bulbectomy and posterior transection of the contralateral lateral olfactory tract. In postoperative tests, experimental rats performed as well as controls when a short intertrial interval (30 seconds) was used but, in contrast to controls, failed to learn a 2-odor discrimination when the intertrial interval was 10 minutes. When tested on a reversal task, controls showed memory for original learning by making many errors while experimental rats quickly acquired the task. The results suggest that lateral olfactory tract afferents to posterior olfactory cortex may play a significant role in short-term memory for odors.

摘要

在单侧嗅球切除术和对侧外侧嗅束后横断联合手术前后，对大鼠进行了一系列新颖的双气味辨别问题训练。在术后测试中，当使用短的试验间隔（30秒）时，实验大鼠的表现与对照组一样好，但与对照组不同的是，当试验间隔为10分钟时，它们未能学会双气味辨别。在反转任务测试中，对照组通过犯许多错误表现出对原始学习的记忆，而实验大鼠则很快掌握了该任务。结果表明，后嗅皮质的外侧嗅束传入纤维可能在气味的短期记忆中起重要作用。