Rogina B, Helfand S L
Department of BioStructure and Function, School of Dental Medicine, University of Connecticut Health Center, Farmington 06030, USA.
Mech Dev. 1997 Apr;63(1):89-97. doi: 10.1016/s0925-4773(97)00033-6.
The spatial and temporal pattern of expression of enhancer trap lines reporting on the wingless (wg) and engrailed (en) genes was characterized in the adult antenna of Drosophila melanogaster. The time courses of expression seen for wg and en, although different from each other, reveal a complex well-controlled pattern of temporal expression, providing evidence that regulatory mechanisms are preserved throughout the life span of the adult fly. Altering the life span demonstrates that the temporal patterns of expression of both wg and en are linked to life span. These studies suggest that the expression of wg and en in the adult antenna is controlled by age-dependent mechanisms.
在黑腹果蝇成虫触角中，对报告无翅（wg）基因和 engrailed（en）基因的增强子陷阱系的表达时空模式进行了表征。wg 和 en 的表达时间进程虽然彼此不同，但揭示了一种复杂且调控良好的时间表达模式，这表明调控机制在成年果蝇的整个寿命期内都得以保留。改变寿命表明，wg 和 en 的表达时间模式都与寿命相关。这些研究表明，成年触角中 wg 和 en 的表达受年龄依赖性机制控制。
