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[化疗与放疗联合治疗局限性霍奇金病。三项MOPP方案化疗试验后的多药化疗预后]

[Chemotherapy-radiotherapy association in the treatment of localized forms of Hodgkin's disease. Prognosis of polychemotherapy after three trials of M.O.P.P].

作者信息

Baillet F, Brun B, Mazeron J J, Rochant H, Pinon G, Reyes F, Vernant J P, Pierquin B, Dreyfus B

出版信息

Nouv Rev Fr Hematol Blood Cells. 1977;18(2):457-61.

PMID:917834
Abstract

63 patients with Hodgkin disease of limited extent (I, II, III) are treated with two protocols: extended field irradiation versus chemotherapy (M.O.P.P.) + extended field irradiation. Three points are suggested by analysis of the results: 1) Advantage from the combination of chemotherapy-radiotherapy. 2) Resistance to chemotherapy frequent innodular sclerosis. 3) In patients treated with chemotherapy the reaction has a prognostic value: failure of treatment being seen only in patients who did not obtain a complete remission.

摘要

63例病变局限(I、II、III期)的霍奇金病患者接受了两种治疗方案:扩大野照射与化疗(MOPP方案)+扩大野照射。通过对结果的分析得出三点:1)化疗与放疗联合的优势。2)结节硬化型对化疗常耐药。3)接受化疗的患者中,反应具有预后价值:仅在未获得完全缓解的患者中出现治疗失败。

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