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霍奇金病脾切除术及腹部探查的指征(作者译)

[Indication for splenectomy and exploration of the abdomen in Hodgkin's disease (author's transl)].

作者信息

Revol R, Alexandre C, Viala J J, Favre-Gilly J

出版信息

Nouv Rev Fr Hematol Blood Cells. 1977;18(2):503-12.

PMID:917839
Abstract

Splenectomies were performed on 142 patients (86 men and 56 women). The majority of them (117) were stages III or IV. The purpose of the laparotomy was therapeutic and not exploratory. Surgery was indicated, either due to evolution of the disease suggesting splenic involvement or to symptoms of hypersplenism. Splenic involvement was confirmed in 71% and hepatic involvement in 40%. Despite the risk of mortality during the first month after surgery, proportional to the extent of the disease, the overall results are encouraging provided that surgical intervention is followed by aggressive polychemotherapy. Serious infections were observed, however, in 9 patients; they did not occur for several months or even several years after splenectomy.

摘要

对142例患者(86例男性和56例女性)实施了脾切除术。其中大多数(117例)为III期或IV期。剖腹手术的目的是治疗性的而非 exploratory(此处原文有误,推测可能是“exploratory”,意为“探索性的”)。手术指征为疾病进展提示脾脏受累或脾功能亢进症状。71%的患者证实有脾脏受累,40%的患者有肝脏受累。尽管术后第一个月存在与疾病程度相关的死亡风险,但如果手术干预后进行积极的多药化疗,总体结果令人鼓舞。然而,9例患者出现了严重感染;这些感染在脾切除术后数月甚至数年都未发生。

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