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用玻璃离子水门汀对天然龋损进行再矿化。

Remineralization of natural carious lesions with a glass ionomer cement.

作者信息

Hatibovic-Kofman S, Suljak J P, Koch G

机构信息

Division of Orthodontics and Paediatric Dentistry, Faculty of Dentistry, University of Western Ontario, London, Canada.

出版信息

Swed Dent J. 1997;21(1-2):11-7.

PMID:9178445
Abstract

Remineralization of carious lesions at the histological level is of great benefit since this will arrest lesion progression. The ability of glass ionomer cement (GIC) to (1) release fluoride it originally contains and (2) release "loosely bound" fluoride acquired from its surroundings have been previously demonstrated. This in vitro study examined the potential for caries remineralization if the lesion was placed near a GIC. Sixteen mesiodistal sections were cut through extracted deciduous molars exhibiting approximal white spot lesions. Sections were "linked" to a plastic tooth restored with a GIC to simulate the abutting surfaces of adjacent teeth. Lesions were photographed in water under polarized light initially and after one- and two-week exposures to artificial saliva. The photographs were digitized, lesion body outlined, and the area corresponding to the body of the lesion was determined to provide a comparison over time. Sixty-two percent of the sections showed a quantitative reduction in lesion body size by an average of 43% after the first week and an additional 14% reduction after the second week. All but two sections demonstrated a qualitative change thereby illustrating that a reduction in pore volume size of the lesion body had also occurred. Therefore, fluoride released from a GIC has the potential to enhance remineralization of the early carious lesion in vitro. The greatest remineralization occurred during the first week of artificial saliva exposure.

摘要

在组织学水平上,龋损的再矿化具有极大益处,因为这将阻止病损进展。玻璃离子水门汀(GIC)(1)释放其原本所含氟化物以及(2)释放从周围环境中获取的“松散结合”氟化物的能力先前已得到证实。这项体外研究考察了若将病损置于GIC附近时龋损再矿化的可能性。对16颗呈现邻面白斑病损的拔除乳牙进行近远中切片。切片“连接”到一颗用GIC修复的塑料牙上,以模拟相邻牙齿的邻接面。最初在水中以及在暴露于人工唾液1周和2周后,在偏振光下对病损进行拍照。将照片数字化,勾勒病损主体轮廓,并确定与病损主体相对应的面积,以便进行随时间的比较。62%的切片显示病损主体大小在第一周后平均定量减少43%,在第二周后又减少14%。除两片切片外,所有切片均显示出定性变化,从而表明病损主体的孔隙体积大小也发生了减小。因此,从GIC释放的氟化物在体外具有增强早期龋损再矿化的潜力。最大程度的再矿化发生在人工唾液暴露的第一周。

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