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衰老鸡脑中糖胺聚糖组成的变化。初步研究。

Changes of glycosaminoglycan composition in aging chicken brain. A preliminary investigation.

作者信息

Pane G, Wegelin I

机构信息

Institute of Histology and General Embryology, University of Bologna.

出版信息

Boll Soc Ital Biol Sper. 1996 Nov-Dec;72(11-12):309-15.

PMID:9178582
Abstract

The qualitative and quantitative pattern of GAGs was examined by electrophoresis in aging chicken brain in four different stages starting from day 1 to 30 months. GAG content referred to defatted dry tissue exhibits constant decrease. Four main GAGs have been identified with a mobility corresponding to hyaluronate, condroitin sulfate, heparan sulfate and dermatan sulfate controls. Hyaluronate appears the main GAG represented while dermatan sulfate the minor one. Our data show that in chicken brain GAG percentage undergoes age-related changes.

摘要

从第1天到30个月的四个不同阶段,通过电泳检测了衰老鸡脑中糖胺聚糖(GAGs)的定性和定量模式。以脱脂干组织计算的GAG含量持续下降。已鉴定出四种主要的GAGs,其迁移率与透明质酸、硫酸软骨素、硫酸乙酰肝素和硫酸皮肤素对照相对应。透明质酸似乎是主要的GAG,而硫酸皮肤素是次要的。我们的数据表明,鸡脑中GAG的百分比会发生与年龄相关的变化。

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