肾小管和肝细胞质膜的糖胺聚糖
Glycosaminoglycans of the plasma membranes of renal tubule and liver cells.
作者信息
Lis D, Monis B
出版信息
J Supramol Struct. 1979;12(1):15-22. doi: 10.1002/jss.400120103.
PMID:120907
Abstract
Glycosaminoglycans were isolated from plasma membranes of hepatic and renal tubule cells of guinea pig. Plasmalemma of renal tubule cells contained more total glycosaminoglycans, hyaluronic acid, chondroitin-4 sulfates and chondroitin-6 sulfates, and less dermatan sulfates and heparin sulfates than liver plasma membranes. These glycocalyx components, owing to their polyanionic properties, may have a role in the transport of water, ions, and macromolecules across the cell membrane.
摘要
从豚鼠肝和肾小管细胞的质膜中分离出糖胺聚糖。肾小管细胞质膜所含的总糖胺聚糖、透明质酸、硫酸软骨素-4和硫酸软骨素-6比肝质膜多，而硫酸皮肤素和硫酸肝素则比肝质膜少。这些糖萼成分由于其聚阴离子特性，可能在水、离子和大分子跨细胞膜的运输中起作用。
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