Melhouf M M, Amrani N, Simony-Lafontaine J, Pujol H, Dubois J B
Service de radiothérapie du Centre régional de lutte contre le cancer Val-d' Aurelle, Montpellier, France.
Bull Cancer. 1997 Feb;84(2):218-22.
We report here 2 cases of breast angiosarcoma observed at Centre Val-d' Aurelle of Montpellier over a period of 14 years (1980 to 1994). Based on a review of literature, we analyze the epidemiological, pathological, clinical, diagnostic and treatment aspects of this rare type of breast cancer. The difficulties of histological diagnosis are underlined. Mastectomy is the treatment of reference. Breast angiosarcoma has the worst prognosis of all mammary malignancies, with a mean survival of 24 months. The low histologic grade and an early diagnosis are the most important factors of good prognosis. The benefit of irradiation and chemotherapy as adjuvant therapy remains to be demonstrated.
我们在此报告蒙彼利埃瓦尔-德-奥雷勒中心在14年期间(1980年至1994年)观察到的2例乳腺血管肉瘤病例。基于文献回顾,我们分析了这种罕见类型乳腺癌的流行病学、病理学、临床、诊断和治疗方面。强调了组织学诊断的困难。乳房切除术是首选治疗方法。乳腺血管肉瘤在所有乳腺恶性肿瘤中预后最差,平均生存期为24个月。低组织学分级和早期诊断是良好预后的最重要因素。放疗和化疗作为辅助治疗的益处仍有待证实。