Cin V G, Celik M, Ulucan S
Selçuk University, School of Medicine, Cardiac Department, Konya, Turkey.
Clin Cardiol. 1997 Jun;20(6):533-5. doi: 10.1002/clc.4960200605.
QT dispersion has been shown to be associated with fatal arrhythmias and sudden death in coronary artery disease. A recent study indicated that marked QT dispersion in electrocardiograms (ECGs) obtained during acute ischemia demonstrated a significant correlation with ventricular fibrillation.
This study investigated the ECG parameters for repolarization (QT dispersion, corrected QT, corrected QT dispersion, and QT dispersion ratio) and their interrelation with acute ischemia.
QT parameters as well as a newly developed repolarization index, QT dispersion ratio [(QT dispersion/RR interval) x 100] were calculated digitally during rest and ischemia in 32 patients with coronary artery disease (rest angina, Braunwald class III). Results were correlated with clinical consequences, mainly arrhythmias, within a follow-up period of 5 +/- 2 days.
While most patients had an increase in all four parameters, only the QT dispersion ratio showed a significant difference when correlated with ventricular arrhythmias (p < 0.001, F ratio = 38).
QT dispersion ratio appears to be a new and promising parameter in predicting ventricular arrhythmias in patients with acute ischemia.
QT离散度已被证明与冠状动脉疾病中的致命性心律失常和猝死相关。最近一项研究表明,急性缺血期间获得的心电图(ECG)中明显的QT离散度与心室颤动显著相关。
本研究调查了复极化的心电图参数(QT离散度、校正QT、校正QT离散度和QT离散度比值)及其与急性缺血的相互关系。
对32例冠状动脉疾病(静息性心绞痛,Braunwald III级)患者在静息和缺血期间数字化计算QT参数以及新开发的复极化指数QT离散度比值[(QT离散度/RR间期)×100]。结果在5±2天的随访期内与临床后果(主要是心律失常)相关。
虽然大多数患者的所有四个参数均增加,但只有QT离散度比值与室性心律失常相关时显示出显著差异(p<0.001,F值=38)。
QT离散度比值似乎是预测急性缺血患者室性心律失常的一个新的且有前景的参数。