Di Federico G, Zezza A, Nicolai M, Lombardi G, Cipollone G, Iantorno R, Boni R, Tenaglia R
Clinica Urologicam, Università G. D'Annunzio, Chieti.
Arch Ital Urol Androl. 1997 Feb;69 Suppl 1:97-100.
PSA half-life was calculated in 37 patients after radical prostatectomy to identify earlier patients with residual disease. The half-life calculated in patients potentially "cured" with absolute PSA values inferior to 0.5 ng/ml after 28 days, was significantly different (P = 0.0008) from the group of patients "uncured" (PSA > 1.0 ng/ml) and from those ones that, despite of detectable PSA level, had evidence of recurrence in the following follow-up. In comparison with the absolute value, the PSA half-life is able to define in the group of patients potentially "cured" those who could have a recurrence in the future.
对37例前列腺癌根治术后患者计算前列腺特异性抗原（PSA）半衰期，以识别早期残留疾病患者。在术后28天绝对PSA值低于0.5 ng/ml且可能“治愈”的患者中计算出的半衰期，与“未治愈”组（PSA>1.0 ng/ml）以及那些尽管PSA水平可检测但在后续随访中有复发证据的患者组相比，差异有统计学意义（P = 0.0008）。与绝对值相比，PSA半衰期能够在可能“治愈”的患者组中确定那些未来可能复发的患者。
