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[血管“重塑”]

[Vascular "remodeling"].

作者信息

Ponte E, Cafagna D, Burri R

机构信息

Cattedra di Angiologia, Università degli Studi, Trieste.

出版信息

Minerva Med. 1997 Apr;88(4):143-9.

PMID:9182257
Abstract

Vascular remodeling means a specific organization of the vascular wall around a diminished lumen as to the before existing conditions, with consequent vascular geometry modification. This organization comes from the response of all vascular components (endothelium, muscular cells, connective component, etc.) to physical and chemical stimuli. Particular behaviour of the vascular wall has lately been pointed out, both in long known pathologies (arteriosclerosis, arterial hypertension, diabetes mellitus, arteriosclerotic aneurysms) and in situations involving both physiopathology (ischaemia-reperfusion, angiogenesis) as therapy (angioplasty).

摘要

血管重塑是指血管壁围绕变窄的管腔进行特定的组织排列,以区别于先前的状态,从而导致血管几何形状发生改变。这种组织排列源于所有血管成分(内皮细胞、肌肉细胞、结缔组织成分等)对物理和化学刺激的反应。最近已指出,在一些早已为人所知的病症(动脉硬化、动脉高血压、糖尿病、动脉硬化性动脉瘤)以及涉及生理病理学(缺血-再灌注、血管生成)和治疗(血管成形术)的情况中,血管壁都有特定表现。

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