[腹膜后和三尖瓣纤维化伴硬皮病样皮肤受累导致水肿，揭示类癌肿瘤。附病例报告及文献复习]

[Edema caused by retroperitoneal and tricuspid fibrosis with sclerodermatous cutaneous involvement disclosing carcinoid tumor. Apropos of a case and review of the literature].

作者信息

Morand J J, Lagrassa S, Abitan R, Koeppel M C, Cohen P, Habib G, Dabeaux-Merger F A, Sayag J

机构信息

Service de dermatologie, hôpital d'instruction des Armées Sainte-Anne, Toulon Naval, France.

出版信息

Rev Med Interne. 1997;18(5):388-95. doi: 10.1016/s0248-8663(97)82510-6.

DOI:10.1016/s0248-8663(97)82510-6

PMID:9183447

Abstract

A 65-year-old female was admitted with leg edema by retroperitoneal fibrosis and tricuspid valve incompetence by fibrosis, cutaneous fibrosis, moderate flushing over the upper body without diarrhea. It revealed an ileal carcinoid tumor with hepatic metastases. Octreotide (Sandostatine), tumor excision and interferon alpha 2b treatment led to a regression of flushing and edema, a reduction of fibrosis and a stabilization of the metastatic carcinoid, with normal serotonin levels.

摘要

一名65岁女性因腹膜后纤维化导致腿部水肿，因纤维化导致三尖瓣关闭不全、皮肤纤维化，上半身中度潮红且无腹泻入院。检查发现患有回肠类癌肿瘤并伴有肝转移。奥曲肽（善得定）、肿瘤切除及干扰素α-2b治疗使潮红和水肿消退，纤维化减轻，转移性类癌病情稳定，血清素水平恢复正常。