Rambaut A, Harvey P H, Nee S
Department of Zoology, University of Oxford, UK.
Comput Appl Biosci. 1997 Jun;13(3):303-6. doi: 10.1093/bioinformatics/13.3.303.
Phylogenetic trees constructed from molecular sequences contain information about the evolutionary or population dynamical processes that created them. Here we describe a computer package (End-Epi) that uses graphical methods to allow researchers to make inferences about these processes from their data. Statistical analyses can be performed to test the consistency of the data with various competing hypotheses.
End-Epi can be obtained by WWW from http://evolve.zoo.ox.ac.uk/ and by anonymous FTP from ftp://evolve.zoo.ox.ac.uk/packages/End-Epi10.hqx. This file contains the compiled application, the manual and a test tree.
从分子序列构建的系统发育树包含了有关产生这些序列的进化或群体动态过程的信息。在此,我们描述了一个计算机程序包(End-Epi),它使用图形方法使研究人员能够根据他们的数据对这些过程进行推断。可以进行统计分析以检验数据与各种相互竞争的假设的一致性。