Down R H, Arnold J, Goldin A, Watts J M, Benness G
Lancet. 1979 Nov 24;2(8152):1094-7. doi: 10.1016/s0140-6736(79)92503-0.
A prospective study of 116 patients admitted as emergencies with a clinical diagnosis of acute cholecystitis or biliary colic has shown that the best investigation for confirming a diagnosis of acute cholecystitis is 99mTc-pyridoxylidene glutamate (PG) scanning. Its sensitivity is 99% and its specificity 86%, whereas those of oral cholecystography are 75% and 82%, respectively, and those of ultrasonography are 54% and 62%, respectively. However, estimation of plasma liver enzymes is essential to exclude acute hepatitis before proceeding to early cholecystectomy.
一项针对116例因临床诊断为急性胆囊炎或胆绞痛而急诊入院患者的前瞻性研究表明，用于确诊急性胆囊炎的最佳检查方法是99m锝-吡哆醛谷氨酸（PG）扫描。其敏感性为99%，特异性为86%，而口服胆囊造影的敏感性和特异性分别为75%和82%，超声检查的敏感性和特异性分别为54%和62%。然而，在进行早期胆囊切除术之前，测定血浆肝酶对于排除急性肝炎至关重要。
