Garnier R
Centre anti-poisons de Paris Hôpital Fernand-Widal, Paris.
Rev Prat. 1997 Apr 1;47(7):736-41.
Liver injury is the main feature of paracetamol poisoning. Early administration of N-acetylcysteine is an effective antidotal treatment. There are also effective treatments for salicylate poisoning and severe cases are always due to delayed diagnosis. Salicylate poisoning should be systematically suspected when several of the following features are observed in a poisoned patient: tinnitus, deafness, hyperventilation, respiratory alkalosis, metabolic acidosis. Diagnosis is readily confirmed by measuring plasma salicylate concentration.
肝损伤是对乙酰氨基酚中毒的主要特征。早期给予N-乙酰半胱氨酸是一种有效的解毒治疗方法。对于水杨酸盐中毒也有有效的治疗方法,严重病例往往是由于诊断延迟。当在中毒患者中观察到以下几种特征时,应系统性怀疑水杨酸盐中毒:耳鸣、耳聋、过度通气、呼吸性碱中毒、代谢性酸中毒。通过测量血浆水杨酸盐浓度很容易确诊。