Sadler T W
University of North Carolina, Department of Cell Biology and Anatomy, UNC Birth Defects Center, Chapel Hill 27599, USA.
Int J Dev Biol. 1997 Apr;41(2):291-7.
Both the metabolic studies on diabetes and the genetic studies using antisense oligodeoxynucleotides clearly demonstrate the importance and usefulness of rodent whole embryo culture. Without this technique, these studies would be impossible and, consequently, our knowledge of both normal and abnormal development would not be as advanced as it is today. The culture system fills a unique niche in studies in the fields of developmental biology and teratology and these sciences would have been less well served without Dr. New's contribution.
对糖尿病的代谢研究以及使用反义寡脱氧核苷酸的遗传学研究均清楚地表明了啮齿动物全胚胎培养的重要性和实用性。没有这项技术，这些研究将无法进行，因此，我们对正常和异常发育的了解也不会像如今这样先进。该培养系统在发育生物学和致畸学领域的研究中占据着独特的地位，若没有纽博士的贡献，这些学科的发展将会受到不利影响。
