Kubota Y, Ueda T, Kagawa Y, Sakai N, Hara A
Department of Neurosurgery, Murakami Memorial Hospital, Asahi University, Gifu.
Neurol Med Chir (Tokyo). 1997 May;37(5):407-10. doi: 10.2176/nmc.37.407.
A 63-year-old female presented with an unusual case of microcystic meningioma manifesting as a 4-year history of unsteady gait, dysarthria, and hearing loss. Computed tomography disclosed a large hypodense mass in the right cerebellopontine angle, clivus, and middle fossa, with slight contrast enhancement. T1-weighted magnetic resonance images demonstrated the lesion as a hypointense mass, which was little enhanced gadolinium-diethylenetriaminepenta-acetic acid. Right carotid angiography revealed blood supply from the external carotid artery, but no tumor staining. The extracerebral tumor was subtotally removed. The histological diagnosis was microcystic meningioma. Light microscopy revealed abundant microcystic throughout the tumor tissue, and electron microscopy disclosed that the microcysts were mostly located in the extracellular spaces and only a few in the cytoplasm. Microcystic meningioma without enhancement is rare and should be differentiated from low-grade astrocytoma, epidermoid, or other non-enhanced tumor.
一名63岁女性，患有罕见的微囊性脑膜瘤，表现为4年的步态不稳、构音障碍和听力丧失病史。计算机断层扫描显示右侧小脑脑桥角、斜坡和中颅窝有一个大的低密度肿块，有轻微的对比增强。T1加权磁共振成像显示病变为低信号肿块，钆双醋二乙三胺五乙酸增强不明显。右侧颈动脉血管造影显示肿瘤由颈外动脉供血，但无肿瘤染色。脑外肿瘤次全切除。组织学诊断为微囊性脑膜瘤。光镜检查显示肿瘤组织内有大量微囊肿，电镜检查显示微囊肿大多位于细胞外间隙，少数位于细胞质内。无强化的微囊性脑膜瘤罕见，应与低级别星形细胞瘤、表皮样囊肿或其他无强化肿瘤相鉴别。
