Fehlmann H U
Schweiz Med Wochenschr. 1977 Aug 27;107(34):1199-202.
The case is reported of a 29-year-old previously healthy female patient who developed the typical clinical picture of scurvy eight months after changing to a diet exclusively containing cooked cereals. Serum levels of B12, folic acid, and calcium were lowered and the alkaline phosphatase was slightly raised due to the dietary lack of vitamins A, D, B12 and folic acid. No clinical signs of these deficiencies could be observed. Addition of vitamin C to this diet resulted in complete cure in a matter of days. Signs and symptoms of scurvy are discussed in the light of the recent literature. This rare disease is particularly worth considering if one of the following situations is encountered: hemorrhages in the skin, muscles, joints or mucous membranes without apparent cause; therapy-resistant ulcers of mucous membranes in elderly patients; Sicca syndrome and/or wounds exhibiting poor healing.
报告了一例29岁既往健康的女性患者，在改为仅食用煮熟谷物的饮食8个月后出现了坏血病的典型临床表现。由于饮食中缺乏维生素A、D、B12和叶酸，血清维生素B12、叶酸和钙水平降低，碱性磷酸酶略有升高。未观察到这些缺乏症的临床体征。在这种饮食中添加维生素C几天后即完全治愈。根据最近的文献讨论了坏血病的体征和症状。如果遇到以下情况之一，这种罕见疾病尤其值得考虑：皮肤、肌肉、关节或粘膜无明显原因出血；老年患者治疗抵抗性粘膜溃疡；干燥综合征和/或伤口愈合不良。
