Morell A, Skvaril F, Spengler G, Barandun S
Schweiz Med Wochenschr. 1977 Oct 15;107(41):1463.
Studies were performed on bone marrow and serum from 28 patients with clinically benign gammopathy and 41 patients with the malignant monoclonal form. In the bone marrow samples, the total number of plasma cells and the monoclonal fraction of these cells were determined by immunofluorescence. Serum samples were analyzed for monoclonal immunoglobulin components and for the total serum protein content. The data could be used for discriminant analysis. The variables had to be transformed and were included in the discriminant function in a stepwise procedure. The resulting function made possible a clear distinction between benign and malignant monoclonal gammopathies.
对28例临床良性丙种球蛋白病患者和41例恶性单克隆形式患者的骨髓和血清进行了研究。在骨髓样本中，通过免疫荧光测定浆细胞总数及其单克隆部分。对血清样本分析单克隆免疫球蛋白成分和总血清蛋白含量。这些数据可用于判别分析。变量必须进行转换，并按逐步程序纳入判别函数。所得函数使得能够明确区分良性和恶性单克隆丙种球蛋白病。
