Shetter A G, Bertuccini T V, Pittman H W
Surg Neurol. 1977 Nov;8(5):341-5.
A retrospective study was performed on 54 patients with intracranial mass lesions who underwent closed needle biopsy using freehand and stereotactic biopsy techniques. A diagnosis of brain neoplasm was established in 44 of 54 patients, and nonneoplastic abnormalities were discovered in an additional six cases. Permanent neurologic worsening was noted in two instances following biopsy, and a single patient died as a result of the procedure. Closed needle biopsy, particulary when done stereotactically, appears to be a resonably safe and efficacious means of establishing a tissue diagnosis in carefully selected patients suspected of harboring a deep-seated supratentorial cerebral neoplasm.
对54例颅内占位性病变患者进行了一项回顾性研究，这些患者采用徒手和立体定向活检技术进行了闭合式针吸活检。54例患者中有44例确诊为脑肿瘤，另外6例发现为非肿瘤性异常。活检后有2例出现永久性神经功能恶化，1例患者因该操作死亡。闭合式针吸活检，特别是立体定向活检，对于精心挑选的疑似患有幕上深部脑肿瘤的患者而言，似乎是一种相当安全有效的组织诊断方法。
