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大鼠肠道粘蛋白RMuc3的羧基末端序列包含一个推定的跨膜区域和两个表皮生长因子样基序。

The carboxyl-terminal sequence of rat intestinal mucin RMuc3 contains a putative transmembrane region and two EGF-like motifs.

作者信息

Khatri I A, Forstner G G, Forstner J F

机构信息

Division of Research Biochemistry, Research Institute, The Hospital for Sick Children and the University of Toronto, Canada.

出版信息

Biochim Biophys Acta. 1997 May 22;1326(1):7-11. doi: 10.1016/s0005-2736(97)00063-1.

DOI:10.1016/s0005-2736(97)00063-1
PMID:9188795
Abstract

A 3' RACE technique was used to establish the nucleotide sequence encoding the C-terminal 379 amino acids of rat intestinal Muc3. Unlike the C-terminus of Muc2 and many secretory mucins, Muc3 contains two EGF motifs and a putative transmembrane domain. The mRNA for rat Muc3 is 7.5-8.0 kb.

摘要

采用3' RACE技术确定了编码大鼠肠道Muc3 C末端379个氨基酸的核苷酸序列。与Muc2和许多分泌性粘蛋白的C末端不同，Muc3含有两个表皮生长因子（EGF）基序和一个推定的跨膜结构域。大鼠Muc3的mRNA为7.5 - 8.0 kb。

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