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[温血动物皮肤衍生物的恢复模式]

[Patterns in the restoration of skin derivatives in warm-blooded animals].

作者信息

Efimov E A

出版信息

Izv Akad Nauk Ser Biol. 1997 Mar-Apr(2):142-8.

PMID:9190217
Abstract

It is known that the skin derivatives in homeothermic animals appear in the early prenatal period of development and do not form during postnatal development. However, during skin regeneration, a process of secondary development, it was shown experimentally on eight homeothermic animals, in which full-layered fragments of skin were removed from different morphofunctional regions of skin, that in the skin regenerates its derivatives are formed: hair, sebaceous and sweat glands, and skin folds. The data obtained suggest that formation of the hair and sebaceous glands requires the presence of special dermal fibroblasts in the young connective tissue of regenerants, which are capable of induction of the potencies of regenerating epidermis for organogenesis.

摘要

已知恒温动物的皮肤衍生物在产前发育早期出现,出生后发育过程中不会形成。然而,在皮肤再生这一二次发育过程中,通过对八只恒温动物进行实验表明,从皮肤不同形态功能区域切除全层皮肤碎片后,再生皮肤中会形成其衍生物:毛发、皮脂腺、汗腺和皮肤褶皱。所获得的数据表明,毛发和皮脂腺的形成需要再生组织年轻结缔组织中存在特殊的真皮成纤维细胞,这些细胞能够诱导再生表皮的潜能进行器官发生。

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