Iurina N A, Radostina A I, Savin B M, Remizova V A, Kosova I P
Aviakosm Ekolog Med. 1997;31(2):43-7.
Effects of single and repeated exposure of mice, rats, and rabbits in magnetic fields at 50 Hz and 2 kA/m, 16 kA/m, and 32 kA/m on the populations of dermal, intestinal, and popliteal lymph node labrocytes were studied immediately and within one month after exposure. Single exposure in the magnetic fields of 2 kA/m and 16 kA/m for 4 hours did not produce any changes in labrocytes of these organs. Repeated exposure to 2 kA/m, 16 kA/m, and 32 kA/m for 4 hours during 5 days modulated the functional activity of labrocytes in all the organs. More extended (1.5-2 months) repeated exposure to the intensive magnetic field (32 kA/m) stimulated adaptation and regain of labrocyte populations in the dermal and popliteal lymph nodes whereas enhanced secretion, i.e. degranulation of labrocytes persisted in the intestine. Following one month after the 1.5-2-month exposure to 32 kA/m, labrocyte populations were recovered with the maximum effect in the lymph nodes. High magnetic sensitivity of labrocytes revealed in this study can be used as a test of body reactivity and adaptation to this physical agent. Differences in the reactivity of labrocytes of individual organs and species must be taken into account.
研究了小鼠、大鼠和兔子单次及重复暴露于50Hz、2kA/m、16kA/m和32kA/m磁场中后,即刻以及暴露后1个月内,其皮肤、肠道和腘窝淋巴结淋巴细胞群的变化情况。在2kA/m和16kA/m磁场中单次暴露4小时,这些器官的淋巴细胞未发生任何变化。在5天内重复暴露于2kA/m、16kA/m和32kA/m磁场中4小时,可调节所有器官中淋巴细胞的功能活性。更长时间(1.5 - 2个月)重复暴露于强磁场(32kA/m)可刺激皮肤和腘窝淋巴结中淋巴细胞群的适应和恢复,而肠道中淋巴细胞的分泌增强,即脱颗粒现象持续存在。在暴露于32kA/m磁场1.5 - 2个月后的1个月,淋巴细胞群得以恢复,在淋巴结中的效果最为显著。本研究中揭示的淋巴细胞的高磁敏感性可作为机体对这种物理因素反应性和适应性的一项检测指标。必须考虑到各个器官和物种的淋巴细胞反应性差异。