Juźwiuk J, Popławski A, Mazerska M, Pawlak K
Kliniki Nefrologii Akademii Medycznej w Białymstoku.
Przegl Lek. 1997;54(1):6-9.
The aim of the study was to follow effects of multiple dialyzer reuse on some coagulation parameters. In a random group of 10 patients undergoing intermittent hemodialysis treatment, platelet coagulant, fibrinogen, BTG and PF4 concentrations were determined after 1st dialyzer usage and after 2 consecutive dialysis sessions after which the dialyzer was reused by manual method with 1% Dialyne solution. An increase in fibrinogen concentration after 240 min of HD procedure was shown when dialyzer was used for 1st and 3rd time. BTG activity increased after 240 min of HI procedure when the dialyzer was used for 3rd time. There was a fall in platelet count after 30 min of HD during the 1st and the 3rd dialyzer use. The fall in platelet count lasted all dialysis session when dialyser was used for 3rd time. The PF4 activity was decreased after 30 min of HD session after the 1st and the 2nd dialyzer use.
本研究的目的是追踪多次复用透析器对某些凝血参数的影响。在一组随机选取的10例接受间歇性血液透析治疗的患者中，在首次使用透析器后以及在连续两次透析治疗后（透析器用1% Dialyne溶液手工复用），测定血小板凝血因子、纤维蛋白原、β-血小板球蛋白（BTG）和血小板第4因子（PF4）的浓度。当透析器首次和第三次使用时，血液透析（HD）程序240分钟后纤维蛋白原浓度升高。当透析器第三次使用时，血液滤过（HI）程序240分钟后BTG活性增加。在首次和第三次使用透析器期间，HD 30分钟后血小板计数下降。当透析器第三次使用时，血小板计数下降持续整个透析过程。在首次和第二次使用透析器后，HD治疗30分钟后PF4活性降低。
