Du Rietz B, Ekman R, Olin T, Olsson A M
Urol Res. 1977;5(3):109-12. doi: 10.1007/BF00256862.
Ligation of the inferior vena cava above the renal veins in male Sprague-Dawley rats produces a predominantly transient renal injury with vascular congestion, tubular degeneration and necrosis with calcification. This is accompanied by impaired renal function with temporary azotaemia, hyperkalaemia, phosphate retention but with a normal calcium level. The parathyroid glands on the second postoperative day show cellular hypertrophy and on the third and fourth days signs of rapid cell proliferation with numerous mitoses. Thereafter the glands remain enlarged.
在雄性斯普拉格-道利大鼠肾静脉上方结扎下腔静脉，会导致主要为短暂性的肾损伤，伴有血管充血、肾小管变性和坏死并钙化。同时伴有肾功能受损，出现暂时性氮血症、高钾血症、磷酸盐潴留，但血钙水平正常。术后第二天甲状旁腺显示细胞肥大，术后第三天和第四天出现细胞快速增殖的迹象，有大量有丝分裂。此后腺体一直肿大。
