Sakata Y, Kodama K, Ishikura F, Komamura K, Hasegawa S, Sakata Y, Hirayama A
Cardiovascular Division, Osaka Police Hospital, Japan.
Jpn Circ J. 1997 May;61(5):455-8. doi: 10.1253/jcj.61.455.
Adjunctive intracoronary administration of nicorandil, an ATP-sensitive potassium channel opener, after successful coronary revascularization was performed in a 54-year-old patient with acute myocardial infarction. The 'no-reflow' phenomenon disappeared after nicorandil administration and significant functional recovery of the infarcted myocardium was achieved. This suggests that nicorandil could eliminate the 'no-reflow' phenomenon after successful coronary revascularization.
对一名54岁急性心肌梗死患者成功进行冠状动脉血运重建后，辅助冠状动脉内注射ATP敏感性钾通道开放剂尼可地尔。注射尼可地尔后，“无复流”现象消失，梗死心肌实现了显著的功能恢复。这表明尼可地尔可消除冠状动脉血运重建成功后的“无复流”现象。
