Hannaway P J, Roundy C
Tufts University School of Medicine, Salem, Massachusetts, USA.
Allergy Asthma Proc. 1997 May-Jun;18(3):177-80. doi: 10.2500/108854197778984383.
Regional analysis of dust mite species distribution is pertinent to clinical practice as atopic patients should be tested and, when indicated, receive appropriate immunotherapy with house dust mite antigens indigenous to their geographic locale. Surveys in selected areas of the United States have found D. farinae and D. pteronyssinus to be the two most prevalent mite species. None of these surveys encompassed the populous Northeastern corridor of the United States. This present study describes the distribution of Dermatophagoides spp. antigens within the homes of asthma sufferers living in suburban Massachusetts. A total of 60 dust samples were collected from carpets in the homes of 46 patients with chronic asthma and documented house dust mite sensitivity. Dust samples were obtained from bedroom carpets in 46 homes and both bedroom and family room carpets in 14 homes. Dermatophagoides spp. bedroom carpet levels ranged from 2.3 ug/g to 138.5 ug/g; (mean level 36.1 ug/g). D. farinae was the dominant species in the majority (78%) of sampled homes. D. pteronyssinus predominated in only three (7%) homes. Nearly 80% of surveyed homes and carpet dust mite antigen levels exceeding 10 ug/g. Mean bedroom carpet levels were more than two-fold higher than family room levels, 47.7 ug/g versus 19.5 ug/g. Distribution patterns of D. farinae and D. pteronyssinus in bedroom and living room carpets was similar in 13 of 14 surveyed homes. Although D. farinae is clearly the dominant allergen in the surveyed homes, this study suggests that both D. farinae and D. pteronyssinus antigens should be used for diagnostic testing and, when indicated, immunotherapy in the northeastern United States.
尘螨物种分布的区域分析与临床实践相关，因为特应性患者应接受检测，并在必要时接受针对其所在地理区域本土屋尘螨抗原的适当免疫治疗。在美国特定地区的调查发现，粉尘螨和屋尘螨是两种最常见的螨类物种。这些调查均未涵盖美国人口密集的东北走廊地区。本研究描述了居住在马萨诸塞州郊区的哮喘患者家中嗜皮螨属抗原的分布情况。共从46例慢性哮喘患者且有记录的屋尘螨敏感性的家中的地毯上采集了60份灰尘样本。灰尘样本取自46户家庭卧室的地毯以及14户家庭卧室和家庭活动室的地毯。嗜皮螨属在卧室地毯中的含量范围为2.3微克/克至138.5微克/克；（平均含量为36.1微克/克）。在大多数（78%）采样家庭中，粉尘螨是优势物种。屋尘螨仅在3户（7%）家庭中占主导地位。近80%的被调查家庭地毯上的尘螨抗原水平超过10微克/克。卧室地毯的平均含量比家庭活动室的含量高出两倍多，分别为47.7微克/克和19.5微克/克。在14户被调查家庭中的13户，卧室和客厅地毯上的粉尘螨和屋尘螨分布模式相似。尽管在被调查家庭中粉尘螨显然是主要过敏原，但本研究表明，在美国东北部，粉尘螨和屋尘螨抗原都应用于诊断检测，并在必要时用于免疫治疗。
