Saldías F, Castellón J M, Garayar B, Blacutt M
Departamento de Enfermedades Respiratorias y Cardiovasculares, Universidad Católica de Chile, Santiago de Chile.
Rev Med Chil. 1996 Aug;124(8):959-66.
Following open heart surgery, most patients are ventilated for 12 to 24 hours to obtain a period of hemodynamic stability and to reduce the work of breathing. Some authors have proposed criteria to guide early extubation and have proposed physiologic parameters to predict which patients will be able to breathe spontaneously.
To study the capacity to predict successful early extubation of ventilatory and gas exchange parameters.
Two hundred thirty patients admitted to an intensive care unit after coronary or valvular surgery were studied. Measurements were made through a T piece 30 minutes after discontinuing mechanical ventilation.
Six patients died in the postoperative period. Two hundred ten patients tolerated early extubation (14 +/- 5 h of mechanical ventilation) and 20 required prolonged mechanical ventilation (74 +/- 107 h). The latter had longer surgical procedures (291 +/- 65 and 240 +/- 67 min respectively) and extracorporeal circulation times (138 +/- 42 and 104 +/- 43 min respectively), required more vasoactive drugs, had more episodes of confusion and had a higher surgical risk. Tidal volume, respiratory frequency, maximal inspiratory pressure and blood gases at the moment of extubation were similar in both groups.
Pulmonary function parameters and blood gases measured during a T piece trial are not good predictors of early extubation in cardiac surgery.
心脏直视手术后,大多数患者需通气12至24小时,以获得一段血流动力学稳定期并减轻呼吸做功。一些作者提出了指导早期拔管的标准,并提出了生理参数来预测哪些患者能够自主呼吸。
研究通气和气体交换参数预测早期拔管成功的能力。
对230例冠状动脉或瓣膜手术后入住重症监护病房的患者进行研究。在停止机械通气30分钟后通过T形管进行测量。
6例患者在术后死亡。210例患者耐受早期拔管(机械通气14±5小时),20例患者需要延长机械通气时间(74±107小时)。后者手术时间更长(分别为291±65和240±67分钟)、体外循环时间更长(分别为138±42和104±43分钟),需要更多血管活性药物,有更多意识混乱发作,且手术风险更高。两组患者拔管时的潮气量、呼吸频率、最大吸气压力和血气相似。
在T形管试验期间测量的肺功能参数和血气不是心脏手术中早期拔管的良好预测指标。