Gatti Giuseppe, Cardu Gabriele, Bentini Corrado, Pacilli Pasqua, Pugliese Peppino
Department of Cardiac Surgery, Villa Torri Hospital, viale Filopanti 12, 40126 Bologna, Italy.
Eur J Cardiothorac Surg. 2004 Apr;25(4):541-7. doi: 10.1016/j.ejcts.2003.12.015.
To determine the predictors of weaning from mechanical ventilation after cardiac operation with the Ciaglia percutaneous dilatational tracheostomy (PDT) in our preliminary experience in the use of this technique.
We prospectively analysed 33 consecutive patients (mean age 70.9+/-12.7 years) who underwent PDT in our intensive care unit after cardiac operation. The investigation involved preoperative and postoperative clinical status, operative procedure, indication and timing for PDT.
PDT was performed after a mean time of 7.7+/-5.0 consecutive days of translaryngeal intubation. Twenty-four (73%) patients were weaned from ventilator after a mean time of mechanical ventilation of 15.8+/-9.1 days. Time point of PDT was the only predictor of ventilator weaning (P=0.0029): there was significant association between PDT performed before the seventh consecutive day of translaryngeal intubation (early PDT) and successful weaning from ventilator (P=0.01; odds ratio=11.2, 95% confidence interval=1.2-104.3). Among the patients weaned from ventilator, those who underwent early PDT had significantly shorter times of mechanical ventilation, and intensive care unit and hospital stays than patients with later PDT (P=0.035, 0.011 and 0.0073, respectively). Nine (27%) patients died of their underlying disease while still being mechanically ventilated; another six (18%) spontaneously breathing but still incannulated patients died afterward. No major PDT-related complications were observed. Two minor peristomal bleedings and one self-resolving subcutaneous emphysema were recorded.
Early PDT was a safe and effective method to wean from mechanical ventilation the cardiosurgical patients of this series.
根据我们使用Ciaglia经皮扩张气管切开术(PDT)的初步经验,确定心脏手术后机械通气撤机的预测因素。
我们前瞻性分析了33例连续患者(平均年龄70.9±12.7岁),这些患者在心脏手术后于我们的重症监护病房接受了PDT。调查涉及术前和术后临床状况、手术操作、PDT的指征和时机。
在经喉插管连续平均7.7±5.0天后进行了PDT。24例(73%)患者在机械通气平均15.8±9.1天后撤机。PDT的时间点是撤机的唯一预测因素(P = 0.0029):在经喉插管连续第7天之前进行的PDT(早期PDT)与成功撤机之间存在显著关联(P = 0.01;优势比 = 11.2,95%置信区间 = 1.2 - 104.3)。在撤机的患者中,接受早期PDT的患者机械通气时间、重症监护病房住院时间和医院住院时间均显著短于接受晚期PDT的患者(分别为P = 0.035、0.011和0.0073)。9例(27%)患者在仍接受机械通气时死于基础疾病;另外6例(18%)自主呼吸但仍带管的患者随后死亡。未观察到与PDT相关的重大并发症。记录到2例轻微的造口周围出血和1例自行消退的皮下气肿。
早期PDT是使本系列心脏手术患者机械通气撤机的一种安全有效的方法。