Grech E S, Mutale E M, Bathirunatham N
Med J Zambia. 1977 Aug-Sep;11(4):99-103.
Fifty patients with acute pelvic inflammatory disease were treated with Alphacillin (Pivampicillin Hcl). The total daily dose consisted of 1050mg, given in three divided doses. Treatment was continued for six days. Full bacteriological investigations were performed. Therapy was continued so long as the condition of the patient improved. In case of failure change to other antibiotics or surgery were considered. The clinical response to Alphacillin was considered successful in 92% of patients. A significant observation in the trial was the low rate of residual pelvic pathology especially in patients with Acute/Chronic pelvic infection. The drug was found to be free from complications or any serious side effects. Mild epigastric discomfort was noticed in only 3 patients.
五十例急性盆腔炎患者接受了氨苄青霉素(盐酸匹氨西林)治疗。每日总剂量为1050毫克,分三次服用。治疗持续六天。进行了全面的细菌学检查。只要患者病情好转,治疗就继续进行。如果治疗失败,则考虑更换其他抗生素或进行手术。92%的患者对氨苄青霉素的临床反应被认为是成功的。该试验中的一个重要观察结果是盆腔残留病变的发生率较低,尤其是在急性/慢性盆腔感染患者中。发现该药物无并发症或任何严重副作用。仅3例患者出现轻度上腹部不适。