Armstrong D G, Lavery L A, Harkless L B, Van Houtum W H
Department of Orthopaedics, University of Texas Health Science Center, San Antonio, USA.
J Am Podiatr Med Assoc. 1997 Jun;87(6):255-9. doi: 10.7547/87507315-87-6-255.
The authors compare the level of foot amputation by age, prevalence of arterial disease as a precipitating factor, gender, and ethnicity in persons with diabetes mellitus. Medical records were abstracted for each hospitalization for a lower extremity amputation from January 1 to December 31, 1993, in six metropolitan statistical areas in south Texas. Amputation level was defined by ICD-9-CM codes and were categorized as foot, leg, and thigh amputations. Foot-level amputations were further subcategorized as hallux or first ray, middle, fifth, multiple digit or ray, and midfoot amputations. Only the highest amputation level for each individual was used in the analysis. Of 1,043 subjects undergoing a lower extremity amputation in south Texas in the year 1993, 477 received their amputation at the level of the foot. African-Americans requiring a foot-level amputation were at significantly higher risk to undergo a midfoot-level amputation than was the rest of the population. Nearly 40% of all subjects undergoing a foot-level amputation had a previous history of amputation. However, nearly 40% of subjects undergoing foot amputations had not been diagnosed either before or during admission with peripheral arterial occlusive disease, suggesting a causal pathway dependent primarily on neuropathy. This implies that better screening of diabetic patients with appropriate risk-directed treatment at the primary care level may significantly impact the large number of preventable diabetes-related lower extremity amputations.
作者比较了糖尿病患者因年龄、作为促发因素的动脉疾病患病率、性别和种族导致的足部截肢水平。对1993年1月1日至12月31日期间在得克萨斯州南部六个大都市统计区因下肢截肢而住院的每位患者的病历进行了摘要分析。截肢水平由ICD-9-CM编码定义,并分为足部、腿部和大腿截肢。足部截肢进一步细分为拇趾或第一跖骨、中间、第五、多趾或跖骨以及中足截肢。分析中仅使用每个个体的最高截肢水平。1993年在得克萨斯州南部接受下肢截肢的1043名受试者中,有477人在足部进行了截肢。需要足部截肢的非裔美国人接受中足截肢的风险明显高于其他人群。所有接受足部截肢的受试者中,近40%有过截肢史。然而,近40%接受足部截肢的受试者在入院前或入院期间未被诊断出患有外周动脉闭塞性疾病,这表明主要依赖神经病变的因果途径。这意味着在初级保健层面更好地筛查糖尿病患者并进行适当的风险导向治疗,可能会对大量可预防的糖尿病相关下肢截肢产生重大影响。