Gregersen H, Ibsen J S, Nielsen M
Aalborg Sygehus, medicinsk-haematologisk afdeling B og klinisk kemisk afdeling.
Ugeskr Laeger. 1997 May 26;159(22):3387-92.
Clinical features, occurrence and reversibility of renal failure, response to treatment and survival duration in 190 multiple myeloma patients were reviewed in a retrospective study based on hospital records. Renal failure was present in 27% of the patients and constituted an important prognostic factor. Reversibility of renal failure occurred in 52% of the patients and was more frequent in those with low serum creatinine, hypercalcaemia, high erythrocyte sedimentation rate and high level of IgA. Response to chemotherapy resulted in a prolonged survival, whereas recovery of renal function did not significantly affect survival.
在一项基于医院记录的回顾性研究中，对190例多发性骨髓瘤患者的临床特征、肾衰竭的发生及可逆性、治疗反应和生存时间进行了评估。27%的患者存在肾衰竭，这是一个重要的预后因素。52%的患者肾衰竭具有可逆性，在血清肌酐水平低、高钙血症、红细胞沉降率高和IgA水平高的患者中更常见。化疗反应使生存期延长，而肾功能恢复对生存无显著影响。
