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[丹麦人群中的子宫切除术。体重相关因素、心理因素和生活方式变量]

[Hysterectomy in a Danish population. Weight-related factors, psychological factors and life style variables].

作者信息

Settnes A, Jørgensen T, Lange A P

机构信息

Københavns Amts Center for Sygdomsforebyggelse, medicinsk afdeling C.

出版信息

Ugeskr Laeger. 1997 May 26;159(22):3408-12.

PMID:9199029
Abstract

The aim was to assess risk factors for hysterectomy performed for benign conditions. In a prevalence study, 2301 Danish women were selected at random in 1982. Information about weight and slimming history, life-styles, psychological factors, gynaecological history, and social background were obtained. In an incidence study, the cohort was followed from 1982 to 1990 to assess the incidence of hysterectomy. In the prevalence study, weight cycling (recurrent weight loss and weight gain of more than 5 kg) was associated with hysterectomy for benign disease (adjusted odds ratio 1.77, 95% confidence interval 1.05-2.99) independently of overweight, smoking, oral contraceptives, psychological and social factors. In the incidence study, weight cycling was the only significant weight-related risk factor for hysterectomy performed for benign disease (adjusted relative risk 2.49, 95% confidence interval 1.10-5.60), explaining the relation between hysterectomy and psychological factors. Weight cycling might be an important risk factor for premenopausal hysterectomy performed for benign conditions.

摘要

目的是评估因良性疾病而行子宫切除术的危险因素。在一项患病率研究中,1982年随机选取了2301名丹麦女性。获取了有关体重及减肥史、生活方式、心理因素、妇科病史和社会背景的信息。在一项发病率研究中,对该队列从1982年至1990年进行随访,以评估子宫切除术的发病率。在患病率研究中,体重波动(反复减重和增重超过5千克)与因良性疾病而行子宫切除术相关(校正比值比为1.77,95%置信区间为1.05 - 2.99),独立于超重、吸烟、口服避孕药、心理和社会因素。在发病率研究中,体重波动是因良性疾病而行子宫切除术唯一显著的体重相关危险因素(校正相对风险为2.49,95%置信区间为1.10 - 5.60),这解释了子宫切除术与心理因素之间的关系。体重波动可能是因良性疾病而行绝经前子宫切除术的一个重要危险因素。

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