Sherman S L, DeFries J C, Gottesman I I, Loehlin J C, Meyer J M, Pelias M Z, Rice J, Waldman I
Department of Genetics, Emory University, Atlanta, GA, USA.
Am J Hum Genet. 1997 Jun;60(6):1265-75. doi: 10.1086/515473.
The field of behavioral genetics has enormous potential to uncover both genetic and environmental influences on normal and deviant behavior. Behavioral-genetic methods are based on a solid foundation of theories and methods that successfully have delineated components of complex traits in plants and animals. New resources are now available to dissect the genetic component of these complex traits. As specific genes are identified, we can begin to explore how these interact with environmental factors in development. How we interpret such findings, how we ask new questions, how we celebrate the knowledge, and how we use or misuse this knowledge are all important considerations. These issues are pervasive in all areas of human research, and they are especially salient in human behavioral genetics.
行为遗传学领域在揭示基因和环境对正常及异常行为的影响方面具有巨大潜力。行为遗传学方法建立在坚实的理论和方法基础之上,这些理论和方法已成功地描绘了动植物复杂性状的组成部分。现在有了新的资源来剖析这些复杂性状的遗传成分。随着特定基因的识别,我们可以开始探索它们在发育过程中如何与环境因素相互作用。我们如何解读这些发现,如何提出新问题,如何宣扬这些知识,以及如何使用或误用这些知识,都是重要的考量因素。这些问题在人类研究的所有领域都普遍存在,在人类行为遗传学中尤为突出。