Hempel V, Haschemian A, Braun U
Anaesthesist. 1975 Aug;24(8):347-8.
In 14 patients undergoing surgery with methoxyflurane anaesthesia the development of metabolic acidosis was observed. As mechanisms causing such acidosis regional ischaemia and inhibition of lactic acid metabolism in the liver by breakdown products of methoxyflurane are discussed.
在14例接受甲氧氟烷麻醉进行手术的患者中,观察到代谢性酸中毒的发生。作为导致这种酸中毒的机制,讨论了局部缺血以及甲氧氟烷分解产物对肝脏乳酸代谢的抑制作用。